Four children have remained free of detectable HIV for more than one year after their antiretroviral therapy (ART) was paused to see if they could experience HIV remission. The children, who acquired HIV before birth, were closely monitored in IMPAACT P1115 for safety and HIV viral suppression. The outcomes reported follow planned ART interruption once the children met predefined virological and immunological criteria. 

• Aidsmap: Some children who start antiretrovirals very early may control HIV after stopping treatment 
• ABC News: 4 children surpass a year of HIV remission after treatment pause: Study 
• HIV.gov: CROI 2024: Dr. Deborah Persaud Discusses Outcomes with HIV Treatment Started Promptly After Birth

Long-acting, injectable antiretroviral therapy (ART) suppressed HIV replication better than oral ART in people who had previously experienced challenges taking daily oral regimens and was found to be safe in adolescents with HIV viral suppression, according to data from ACTG 5359 (LATITUDE) and IMPAACT 2017 (MOCHA) presented at CROI. 

• Medriva: Breakthrough in HIV Treatment: Injectable ART Proves Highly Effective for Adolescents
• HIV.gov: Long-Acting HIV Treatment Benefits Adults with Barriers to Daily Pill Taking and Adolescents with Suppressed HIV